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Welcome to NPInter |
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NPInter
is a new database covering eight category functional interactions between noncoding RNAs (except tRNAs and rRNAs) and proteins related biomacromolecules (proteins, mRNAs and genomic DNAs) in six model organisms.
By functional interactions, we mean both physical interactions between the ncRNA and protein, and other forms of interaction where the combination of an ncRNA and an mRNA or a genomic DNA sequence elicits a cellular reaction.
This database is distinguished from other biomolecular interaction database by:
- The data of NPInter is novel, in the sense that no earlier database has especially cataloged this type of data (ncRNA-protein interactions). The database now contains more than 700 published functional interactions from the six organisms E. coli, yeast, worm, fly, mouse and human in which functional interactions experiments have been concentrated. The amount of data is not large, but the NPInter covers almost all experimentally verified ncRNA functional interaction data which had been published before the end of last year.
- The ncRNA functional interaction data are entered into NPInter only following publication in books or peer-reviewed journals. Entry is done manually by a curator, and thereafter double-checked by a second curator.
- We introduce a classification of the functional interaction data, which is based on the functional interaction process the ncRNA takes part in.
- NPInter also provides an efficient search option, allowing recovery of interactions, related publications and other information.
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