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 赵 屹

Name: Last:Yi First:Zhao
AGE: 28
Gender: Male
Date of Birth: 1973.09.08
NATIONALITY: Chinese
Tel: (8610)62565522-5717
E-mail: biozy@ict.ac.cn

Education Background:
1997--2000: Graduate Student (M.S) Dept. of Immunology, Peking University Heath Science Center (Beijing)
1990--1995: Medical student (M.D) Beijing University of Chinese Medicine (Beijing)

Working Experience:
2000.07-Present: Bioinformatcis Lab, Key Laboratory of Intelligent Information Processing , Institute of Computing Technology , Chinese Academy of Sciences
1995--1997: Resident doctor Clinical Research Center, Dept. of Surgery 1st Tech Hospital of Beijing University of Chinese Medicine(Beijing)

Teaching Experience:
1997--1999: Teaching Assistant Dept. of Immunology, School of Medicine Science, Peking University Heath Science Center, Beijing
1995--1997: Teaching Assistant Clinical Research Center, Dept. of Surgery 1st Tech Hospital of Beijing University of Chinese Medicine (Beijing)

Research Experience:
2000--Present:Bioinformatics Lab. Key Laboratory of Intelligent Information Processing, Institute of Computing Technology ,Chinese Academy of Sciences Project:Human Genome Analysis
1997--2000: T Cell Research Laboratory, Dept. of Immunology, Peking University Heath Science Center, Beijing
◇1998--2000: Project: Separation, purification and identification of PF18-3 molecule, a novel thymocyte apoptosis-associated molecule.
Experimental Techniques:Gel size chromatography, Ion change chromatography,Affinity chromatography,FPLC, SDS-PAGE,Western blot,Immunoprecipitation, Monoclonal antibody production,and Some Routine Immunological techniques;Cell culture, Handling of laboratory animals; Antigen and antibody analysis by immunohistochemistry; Flow cytometry analysis; Analysis of Cell apoptosis by TUNNEL,FACS,DNA ladder.
◇1998-1999: Project: Study of Expression of MAGE-1,-4,-10 and NY-ESO-1 gene in Human Hepatocellular Carcinoma.
Experimental Techniques:genomic DNA and total RNA extraction;RT-PCR,Southern blot and so on.
◇1997-1999: Project: Molecular Cloning of T Cell Development ----Related Genes and the Expression of Recombinant Protein: gene cloning of TDRM-1 (the GenBank accession number is AF251787)
Experimental Techniques:Construction of cDNA expression library, library screening, new gene cloning,Northern blot,RT-PCR,RACE,the expression of recombinant proteins in prokaryotic expression systems Bioinformatics Methods:such as biomedical databases searching; function prediction of novel gene;genomic DNA and cDNA analysis.

Publications:
[1]Topological structure analysis of the protein-protein interaction network in budding yeast. Nucleic Acids Research, 2003, Vol.31,No.9 2443-2450
[2]蛋白复合物与相互作用谱和表达谱底相关性分析. 科学通报 第48卷第18期 2003年9月
[3]Analysis of correlations between protein complex and protein-protein interaction and mRNA expression. Chinese Science Bulletin 2003 Bol.48 No.20 2226-2230
[4]siRNA Designs to The Crucial Proteins of SARS Coronavirus 生物化学与生物物理进展 2003;30(3)
[5] Yi Zhao,Hai-Tao Zhao,et al. Expression and clinical application of MAGE-1 gene in in Human Hepatocellular Carcinoma Modern Surgery 1999.12.5 (4)
[6] Hai-Tao Zhao, Yi Zhao,et al, Antony W. Burgess, Weifeng Chen. Expression of NY-ESO-1 gene in Human Hepatocellular Carcinoma (in preparation)
[7] Yi Zhao, Weifeng Chen. Gene Cloning and Function Predictions of HDGF-like gene,TDRM-1 in mouse thymus.(In Preparation)
[8] Yi Zhao, Yingwang, Yan li,Weifeng Chen. Separation, purification and identification of PF18-3 molecule, a novel thymocyte apoptosis- associated molecule. (In preparation)

Honor:
1999: Award for Excellent Graduate Student (Peking University Heath Science Center)
1993: Award for College Student (Ren-min Fellowship) (Beijing University of Chinese Medicine)


 


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