Glycolysis
An
Overview: Glycolysis Has Two Phases
The
Preparatory Phase of Glycolysis Requires ATP
The Payoff
Phase of Glycolysis Produces ATP
Fates of Pyruvate
under Aerobic and Anaerobic Conditions
BOX 14-1 Glycolysis
without Oxygen: Alligators and Coelacanths
BOX 14-2 BREWING
BEER
Ethanol Is
the Reduced Product in Alcohol Fermentation
Thiamine
Pyrophosphate Carries "Active Aldehyde"
Groups
Feeder Pathways
for Glycolysis
Other
Monosaccharides Can Enter the Glycolytic Pathway
Dietary
Disaccharides Are Hydrolyzed to Monosaccharides
Regulation of
Carbohydrate Catabolism
Regulatory
Enzymes Act as Metabolic Valves
Liver
Glycogen Phosphorylase Is Regulated by Hormones
and Blood Glucose
Hexokinase
Is Allosterically Inhibited by Its Product
BOX 14-3
Isozymes: Different Proteins That Catalyze the Same
Reaction
Pyruvate
Kinase Is Inhibited by ATP
Phosphofructokinase-1
Is under Complex Allosteric Regulation
Glycolysis
and Gluconeogenesis Are Coordinately Regulated
Secondary
Pathways of Glucose Oxidation
Oxidative
DecarBOXylation Yields Pentose Phosphates and
NADPH
Glucose
Is Converted to Glucuronic Acid and Ascorbic Acid
Summary
Further Reading
Problems
