Gene Regulation:
Principles and Proteins
The
Activity of RNA Polymerase Is Regulated
Transcription
Initiation Is Regulated by Proteins Binding to or
near Promoters
Many
Prokaryotic Genes Are ftegulated in Units Called
Operons
The lac
Operon Is Subject to Negative ftegulation
Regulatory
Proteins Have Discrete DNA-Binding Domains
Regulatory
Proteins Also Interact with Other Proteins
Regulation of Gene
Expression in Prokaryotes
The lac
Operon Is Also Subject to Positive Regulation
The ara
Operon Undergoes Both Positive and Negative
Regulation by a Single Regulatory Protein
Genes for
Amino Acid Biosynthesis Are Regulated by
Transcription Attenuation
Induction
of the SOS Response Requires the Destruction of
Repressor Proteins
Bacteriophage
? Provides an Example of a Regulated
Developmental Switch
Synthesis
of Ribosomal Proteins Is Coordinated with rRNA
Synthesis
Some
Genes Are Regulated by Genetic Recombination
Regulation of
Gene Expression in Eukaryotes
Transcriptionally
Active Chromatin Is Structurally Distinct
Most
Eukaryotic Promoters Are Positively Regulated
Development
Is Controlled by a Cascade of Regulatory Proteins
Summary
Further Reading
Problems
